报告题目：Translational Control at the Start Codon: from ribosome dynamics to mRNA methylation

　　报 告 人：SHUBING QIAN Associate Professor，美国康奈尔大学

　　报告时间：2017年4月19日（星期三）上午 10:00

　　报告地点：中科院生物物理所图书馆二楼报告厅

　　主 持 人：秦燕 研究员

　　报告人简介：

　　EDUCATION

　　2004 – 2008 Postdoc University of North Carolina at Chapel Hill Cell Biology Advisor: Dr. Cam Patterson

　　2000 – 2004 Postdoc National Institutes of Health, NIAID Cell Biology Advisor: Dr. Jonathan W. Yewdell

　　1997 – 2000 Ph.D. Shanghai Jiaotong University Biochemistry Advisor: Dr. Shi‐Shu Chen

　　1994 – 1997 M.Sc. Shanghai Jiaotong University Molecular Biology

　　ACADEMIC APPOINTMENTS

　　2014 – Present Associate Professor Division of Nutritional Sciences, Cornell University, Ithaca, NY

　　2008 – 2014 Assistant Professor Division of Nutritional Sciences, Cornell University, Ithaca, NY

　　近期发表文章：

　　PUBLICATIONS

　　1. Saikia M*, Wang X, Mao Y, Wan J, Pan T and Qian SB*. Codon optimality controls differential mRNA translation during amino acid starvation. RNA 2016; 22(11):1719‐1727

　　2. Liu B and Qian SB*. Characterizing inactive ribosomes in translational profiling. Translation 2016 4(1):e1138018

　　3. Qian SB. Step back for seminal translation. Nat Struct Mol Biol 2016; 232(5):362‐3

　　4. Zhou J, Rode KA, and Qian SB*. m6A: A novel hallmark of translation. Cell Cycle 2015; 10:1‐2

　　5. Meyer KD, Patil DP, Zhou J, Zinoviev A, Skabkin MA, Elemento O, Pestova TV, Qian SB and Jaffrey SR. 5ʹ UTR m6A promotes cap‐independent translation. Cell 2015; 163(4):999‐1010

　　6. Zhou J, Wan J, Gao, X, Zhang X and Qian SB*. Dynamic m6A mRNA methylation directs translational regulation of heat shock response. Nature 2015; 526(7574):591‐4

　　 Highlighted in Nat Chem Biol Recommended by Faculty 1000

　　7. Gao X, Wan J, and Qian SB*. Genome‐wide profiling of alternative translation initiation sites. Methods Mol Biol 2016;1358:303‐16